header image Professor Hakim Dilshad Hussain Tabssum (Gold Medalist) Ex-member: American Infertility Association (USA)
 
 

Hypogonadism

female hypogonadism

(JUMP ) Herbal treatment for Female Hypogonadism

What is Female  Hypogonadotropic Hypogonadism?

1.   Hypogonadism occurs when your sex glands produce little or no sex hormones. The sex glands, also called gonads, ovaries in women. Sex hormones help control sex characteristics, such as breast development, and pubic hair growth. Sex hormones also play a role in menstrual cycles 

2.  Hypogonadotropic Hypogonadism is a health condition developed because of absent or decreased function of the ovaries due to a problem with the pituitary or hypothalamus gland – decreased production of a hormone called “Gonadotropin-Releasing Hormone. The Gonadotropin-Releasing Hormone is needed for stimulation of ovaries to produce sex hormones.  Absence and or deficit of  is the main cause for development of all clinical symptoms of Hypogonadotropic Hypogonadism. During Hypogonadotropic Hypogonadism ovaries produce little or no sex hormones. Hypogonadotropic Hypogonadism sometimes could be called Gonadotropin deficiency, Secondary hypogonadism and or Kallmann syndrome.In general girls with Hypogonadotropic Hypogonadism do not reach puberty, have small size of ovaries and are not able to become pregnant (primary infertility). Females with Hypogonadotropic Hypogonadism have abnormal ovaries that do not produce normal levels of sex hormones which are needed for normal puberty development and for normal menstrual cycles. Actually all girls with Hypogonadotropic Hypogonadism have primary amenorrhea (absence of periods). Most cases of hypogonadotropic hypogonadism are inherited.
 

 cases of hypogonadotropic hypogonadism 

It is well known that in healthy females the hypothalamus in the brain releases Gonadotropin-Releasing Hormone  which stimulates the pituitary gland to release hormones called “Luteinizing Hormone (LH)” and “Follicle-Stimulating Hormone (FSH)”. These hormones are responsible for hormone production in ovaries (mainly sex hormones). And ovarian sex hormones are responsible for normal sexual development in puberty including development of the regular menstrual cycle. The disruption in this chain of the step-by-step hormones production causing the deficiency of the sex hormones and preventing normal sexual maturity.
Failure of the hypothalamus is most common cause of so called “Kallmann syndrome” which is an inherited form of Hypogonadotropic Hypogonadism that can be associated with a loss of smell.

If the Hypogonadotropic Hypogonadism inherited or develops before puberty, it prevents normal sexual maturity.

If the Hypogonadotropic Hypogonadism   occurs after puberty, sexual development may be normal, but the client could have symptoms of low sex hormones – similar like menopause symptoms.

Hypogonadotropic Hypogonadism Symptoms

 

Lack of development during puberty is a main cause of all symptoms typical for hypogonadotropic hypogonadism. Main symptom of hypogonadotropic hypogonadism is AMENORRHEA (absence of periods) which is a result of incomplete hormonal development during puberty.

Unfortunately amenorrhea is not only symptom of hypogonadotropic hypogonadism. Most common symptoms of hypogonadotropic hypogonadism include the following:

  • Amenorrhea (absence of menstrual periods);
  • Incomplete sexual maturation
  • Absence of secondary sexual characteristics such as pubic and underarm hair;
  • Underdeveloped breasts and/or shrinking of breasts;
  • Short stature (in some cases);
  • Inability or reduced ability to smell (in some cases);
  • Pain during sexual intercourse;
  • Underdeveloped and dry vagina (lack of lubrication);
  • Infertility;
  • Loss of bone mass (osteoporosis);
  • Decreased libido;
  • Hot flashes;
  • Sleep disturbances;
  • Symptoms of urinary bladder discomfort (frequent urination, frequent urinary infections);
  • Heart disease (sometimes).

Hypogonadotropic Hypogonadism diagnosis

Diagnosis of the hypogonadotropic hypogonadism is not complicated and should be done in specialized clinics. Few tests could be enough for final diagnosis:

  • Blood tests for main female hormones;
  • So called “LH test” (Luteinizing hormone test) – LH response to Gonadotropin-releasing hormone (GnRH)
  • Magnetic resonance imaging (MRI) of the head for excluding the noncancerous growth in the pituitary gland

 

Hypogonadotropic Hypogonadism Solutions

 
Only solution for hypogonadotropic hypogonadism is hormonal replacement therapy which includes all needed female hormones which can insure proper development. As soon hormonal replacement starts, sooner and better the results could be.
Modern treatment of the hypogonadotropic hypogonadism could include hormonal pills, injections and/or slow-release skin patches.
In case of pituitary tumors surgical treatment would be required.
 

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